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The way to Use Progesterone

Earlier than you think about using progesterone, it is very important perceive that it isn’t a magic bullet, and that you just get probably the most profit by implementing a Bioenergetic eating regimen method that permits you to successfully burn glucose as your major gasoline with out backing up electrons in your mitochondria that reduces your power manufacturing. My new e book, “Your Information to Mobile Well being: Unlocking the Science of Longevity and Pleasure” comes out very quickly and covers this course of in nice element.

After getting dialed in your eating regimen, an efficient technique that may assist counteract estrogen extra is to take transmucosal progesterone (i.e., utilized to your gums, not oral or transdermal), which is a pure estrogen antagonist. Progesterone is considered one of solely 4 hormones I imagine many adults can profit from. (The opposite three are thyroid hormone T3, DHEA and pregnenolone.)

I don’t suggest transdermal progesterone, as your pores and skin expresses excessive ranges of 5-alpha reductase enzyme, which causes a good portion of the progesterone you take to be irreversibly transformed primarily into allopregnanolone and can’t be transformed again into progesterone.

Preferrred Option to Administer Progesterone

Please observe that when progesterone is used transmucosally in your gums as I counsel, the FDA believes that by some means converts it right into a drug and prohibits any firm from advising that on its label. This is the reason firms like Well being Natura promotes their progesterone merchandise as “topical.”

Nonetheless, please perceive that it’s completely authorized for any doctor to suggest an off-label indication for a drug to their affected person. On this case, progesterone is a pure hormone and never a drug and could be very protected even in excessive doses. That is in contrast to artificial progesterone referred to as progestins which are utilized by drug firms, however continuously, and incorrectly, referred.

Dr. Ray Peat has finished the seminal work in progesterone and possibly was the world’s best skilled on progesterone. He wrote his Ph.D. on estrogen in 1982 and spent most of his skilled profession documenting the necessity to counteract the risks of extra estrogen with low LA diets and transmucosal progesterone supplementation.

He decided that the majority solvents don’t dissolve progesterone effectively and found that vitamin E is the perfect solvent to optimally present progesterone in your tissue. Vitamin E additionally protects you towards injury from LA. You simply have to be very cautious about which vitamin E you utilize as most supplemental vitamin E available on the market is worse than nugatory and can trigger you hurt not profit.

It’s crucial to keep away from utilizing any artificial vitamin E (alpha tocopherol acetate — the acetate signifies that it is artificial). Pure vitamin E might be labeled “d alpha tocopherol.” That is the pure D isomer, which is what your physique can use.

There are additionally different vitamin E isomers, and also you need the entire spectrum of tocopherols and tocotrienols, particularly the beta, gamma, and delta varieties, within the efficient D isomer. For example of a perfect vitamin E, you’ll be able to have a look at the label on our vitamin E in our retailer. You should use any model that has an identical label.

You should buy pharmaceutical grade bioidentical progesterone as Progesterone Powder, Bioidentical Micronized Powder, 10 grams for about $40 on many on-line shops like Amazon. That’s almost a yr’s provide, relying on the dose you select.

Nonetheless, you will want to buy some small stainless-steel measuring spoons as you will want a 1/64 tsp, which is 25 mg and a 1/32 tsp, which is 50 mg. A standard dose is usually 25-50 mg and is taken half-hour earlier than mattress, because it has an anti-cortisol operate and can improve GABA ranges for night time’s sleep.

Sadly, this vendor continuously runs out of product, and if that’s the case, then you need to use Merely Progesterone by Well being Natura. It’s premixed with vitamin E and MCT oil. Once more, whereas Well being Natura states that its product is for “topical use solely,” I like to recommend making use of it transmucosally, by rubbing it in your gums.

If you’re a menstruating lady, it is best to take the progesterone through the luteal part or the final half of your cycle, which may be decided by beginning 10 days after the primary day of your interval and stopping the progesterone when your interval begins.

If you’re a male or non-menstruating lady, you’ll be able to take the progesterone every single day for 4 to 6 months after which cycle off for one week. One of the best time of day to take progesterone is half-hour earlier than mattress because it has an anti-cortisol operate and can improve GABA ranges for night time’s sleep.

That is what I’ve been personally doing for over a yr with excellent outcomes. I’m a doctor so should not have any issues doing this. In case you aren’t a doctor, it is best to seek the advice of one earlier than utilizing this remedy, as transmucosal progesterone remedy requires a health care provider’s prescription.